Tyler Bowman, Nagma Vohra, Keith Bailey, Magda O. El-Shenawee
https://www.spiedigitallibrary.org/journals/Journal-of-Medical-Imaging/volume-6/issue-2/023501/Terahertz-tomographic-imaging-of-freshly-excised-human-breast-tissues/10.1117/1.JMI.6.2.023501.short?SSO=1
Terahertz imaging and spectroscopy
characterization of freshly excised breast cancer tumors are presented in the
range 0.15 to 3.5 THz. Cancerous breast tissues were obtained from partial
or full removal of malignant tumors while healthy breast tissues were obtained
from breast reduction surgeries. The reflection spectroscopy to obtain the
refractive index and absorption coefficient is performed on experimental data
at each pixel of the tissue, forming tomographic images. The transmission
spectroscopy of the refractive index and absorption coefficient are retrieved
from experimental data at few tissue points. The average refractive index and
absorption coefficients for cancer, fat, and collagen tissue regions are
compared between transmission and reflection modes. The reflection mode offers
the advantage of retrieving the electrical properties across a significantly
greater number of points without the need for sectioning or altering the
freshly excised tissue as in the transmission mode. The terahertz spectral
power images and the tomographic images demonstrated good qualitative
comparison with pathology.
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