Abstract-Gastrointestinal cancer diagnostics by terahertz time domain spectroscopy

Anna Goryachuk.  Anna Simonova,   Mikhail Khodzitsky,  Mariia Borovkova,  Abdo Khamid,

http://ieeexplore.ieee.org/document/7985863/

Samples of fresh excised tissues obtained from patients who had undergone gastric cancer have been investigated. Samples consisted of cancer zone, normal zone and pathologically changed zone. Their optical properties and spectral features were investigated by terahertz time-domain spectroscopy (THz-TDS) in reflection mode. It was found that waveforms of reflected signals from normal and cancer tissues and their optical properties were well distinguished, so it can be concluded that it is possible to discriminate gastric cancer tissue from normal by using THz-TDS.

Abstract-Investigation of terahertz radiation influence on rat glial cells

Mariia Borovkova, Maria Serebriakova, Viacheslav Fedorov, Egor Sedykh, Vladimir Vaks, Alexander Lichutin, Alina Salnikova, and Mikhail Khodzitsky

https://www.osapublishing.org/boe/abstract.cfm?uri=boe-8-1-273

We studied an influence of continuous terahertz (THz) radiation (0.12 – 0.18 THz, average power density of 3.2 mW/cm2) on a rat glial cell line. A dose-dependent cytotoxic effect of THz radiation is demonstrated. After 1 minute of THz radiation exposure a relative number of apoptotic cells increased in 1.5 times, after 3 minutes it doubled. This result confirms the concept of biological hazard of intense THz radiation. Diagnostic applications of THz radiation can be restricted by the radiation power density and exposure time.

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