Abstract-Study of protein conformation change induced by pH condition using terahertz spectroscopy

Jun Zhou, Xin Rao, Junhong Tian,  Jiafu Wang, Tao Li,

https://ieeexplore.ieee.org/document/8068501/

The terahertz absorption spectra of BSA (Bovine Serum Albumin) in aqueous solution were measured under different pH values from 2.2 to 8. The absorption spectra were analyzed using the two-dimensional correlation spectroscopy (2DCOS). By comparing the cross peaks corresponding to the different pH values, it can be obtained that the conformation is related to the pH condition.

Abstract-Classification of radix angelicae dahuricae from different regions by terahertz spectroscopy

Junhong Tian, Jiafu Wang, Jun Zhou,  Guihua Jiang, Yuying Ma

https://ieeexplore.ieee.org/document/8068499/

In this work, terahertz time-domain spectroscopy was employed to establish the fingerprints of Radix Angelicae Dahuricae (RAD). Principal component analysis (PCA) and k-subspace clustering were employed to study the similarities and dissimilarities among the 120 RAD samples. The methods can be successfully used to classify these samples according to their regions. The results show that the referred technologies can be efficiently used to classify RAD into groups, which provides a method for pattern recognition of other traditional Chinese medicine.