Abstract-Glycerol dehydration of native and diabetic animal tissues studied by THz-TDS and NMR methods

O. A. Smolyanskaya, I. J. Schelkanova, M. S. Kulya, E. L. Odlyanitskiy, I. S. Goryachev, A. N. Tcypkin, Ya. V. Grachev, Ya. G. Toropova, and V. V. Tuchin

https://www.osapublishing.org/boe/abstract.cfm?uri=boe-9-3-1198&origin=search

The optical clearing method has been widely used for different spectral ranges where it provides tissue transparency. In this work, we observed the enhanced penetration of the terahertz waves inside biological samples (skin, kidney, and cornea) treated with glycerol solutions inducing changes of optical and dielectric properties. It was supported by the observed trend of free-to-bound water ratio measured by the nuclear magnetic resonance (NMR) method. The terahertz clearing efficiency was found to be less for diabetic samples than for normal ones. Results of the numerical simulation proved that pulse deformation is due to bigger penetration depth caused by the reduction of absorption and refraction at optical clearing.

© 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

Abstract-Experimental and theoretical study of DNA gyrotropy at THz frequencies

A.V. Semenov,   Yu. Yu. Choporova,   O.P Cherkasova,  V. L. Vaks,  O. A. Smolyanskaya,

http://ieeexplore.ieee.org/document/8067200/

The theoretical calculations predicted shift of the absorption spectra of DNA solution in lower frequencies from B- to A-form. The experiments were carried out for DNA dissolved in water and 25% ethanol. Two different technique, THz time domain spectroscopy and THz ellipsometry at NovoFEL facility, were applied for measuring difference in dielectrical properties caused by conformational transmission.

Abstract-Features of the terahertz spectra of iron oxide nanoparticles in a silicon dioxide shell and of iron oxide and hydroxide nanoparticles

V. Afonin, N. S. Balbekin, G. Z. Gareev, K. G. Gareev, A. N. Gorshkov, D. V. Korolev, V. V. Luchinin, and O. A. Smolyanskaya

https://www.osapublishing.org/jot/abstract.cfm?uri=jot-84-8-515

New methods have been developed for noninvasive monitoring of pathological processes in a living organism by means of terahertz spectroscopy and visualization using contrast agents based on magnetic nanoparticles. The nanoparticles must possess good magnetic characteristics, must be nontoxic and stable against aggregation, and must exhibit chemical stability; therefore, they are enclosed in a biologically inert shell. This paper discusses the spectral features of iron oxide nanoparticles in a biologically inert shell consisting of silicon dioxide and nanoparticles of iron oxide and hydroxide in the terahertz frequency range. It is shown that the crystalline phase of iron oxide can be identified for both types of nanoparticles by means of terahertz spectroscopy.

© 2017 Optical Society of America