Wednesday, November 21, 2018

Abstract-High-sensitivity and label-free identification of a transgenic genome using a terahertz meta-biosensor


Yuping Yang, Dongqian Xu, and Weili Zhang

https://www.osapublishing.org/oe/abstract.cfm?uri=oe-26-24-31589

A high-sensitivity and label-free method for identifying a transgenic plant genome is highly desirable in plant biotechnology. Here, we present a terahertz (THz) metamaterial (MM)-based biosensor that comprises a planar array of gold split-ring (SR) resonators capable of sensing a considerable shift in the resonance frequency due to the change of the dielectric environment on the MM chip. The meta-sensor is employed to detect transgenic tomato genome DNAs by THz time-domain spectroscopy. The experimental results were confirmed by finite-element modeling through varying the thickness and dielectric constant of the DNA overlayer. Consequently, high-efficiency and label-free discrimination between the wild-type and transgenic genome DNA was achieved.
© 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

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