Abstract-The Application of Terahertz Spectroscopy to Protein Detection: A Review

Lijuan Xie^a, Yang Yao^a & Yibin Ying^a*

http://www.tandfonline.com/doi/abs/10.1080/05704928.2013.847845

Applied Spectroscopy Reviews

Volume 49, Issue 6, 2014, pages 448- 461
Available online: 20 Dec 2013

DOI: 10.1080/05704928.2013.847845

Abstract

Terahertz (THz) technology is a recent promising technology that plays an important role in various areas, including national defense, military, materials, chemistry, medicine, pharmaceutical, communications, and many other fields. In this article, the application of terahertz spectroscopy to protein detection is reviewed. The theoretical foundation of terahertz technology in protein detection is explained. In addition, research on protein conformational changes and molecular interactions is reviewed. Subsequently, the quantitative analysis of protein content is introduced. In addition, existing challenges and solutions are discussed.