Equine Veterinary Journal, 2013, 45, 470-475
E. J. McConnell, E. Rioja, L. Bester, M. G. Sanz, G. T. Fosgate, M. N. Saulez
Abstract: Near-infrared spectroscopy (NIRS) was used to identify trends in regional cerebral oxygen saturation (rSO2) in horses and establish a correlation between rSO2 and venous oxygen tensions. A cerebral oximeter sensor recorded rSO2 from the dorsal sagittal sinus of 6 healthy horses. Values for rSO2, arterial and venous oxygen and carbon dioxide tensions (PaO2, PvO2, PaCO2 and PvCO2 respectively), along with arteriovenous oxygen saturations (SavO2) were recorded in unsedated (recording period [RP] 1), sedated (RP2) and anaesthetised horses (RP3–5) and during recovery (RP6–8). During anaesthesia, horses were ventilated to achieve states of normo- (RP3), hyper- (RP4) and hypocapnoea (RP5). Data were evaluated descriptively and analysed using linear mixed-effects models and Pearson's correlation coefficient. Overall mean ± s.d. values for rSO2, PaO2, PvO2, PaCO2, SavO2 and mean arterial pressure varied significantly by RP (P<0.001). Significant decreases in rSO2 were identified between RP1 and the post anaesthetic periods (P<0.001). No significant differences in rSO2 values were identified between RP1 and the intra-anaesthesia periods or between RP3, RP4 and RP5. Significant correlations were identified between rSO2 and PaO2 (r = 0.448, P<0.001), rSO2 and PvO2 (r = 0.512, P<0.001) and rSO2 and SavO2 (r = 0.469, P<0.001). This is the first study to identify trends in rSO2 in horses using NIRS. A positive correlation was identified between rSO2 and PvO2, suggesting that alterations in cerebral oxygenation may be reflected in PvO2.
- This paper is free to view for all users registered on spectroscopyNOW.com until the end of August 2013.After this time, you can purchase it using Pay-Per-View on Wiley Online Library.
- Click here to access the abstract of this paper >>>
From the abstract page you can progress to read the full paper.
No comments:
Post a Comment