Abstract-Terahertz refractive index-based morphological dilation for breast carcinoma delineation

 

Quentin Cassar, Samuel Caravera, Gaëtan MacGrogan, Thomas Bücher, Philipp Hillger, Ullrich Pfeiffer, Thomas Zimmer, Jean-Paul Guillet,  Patrick Mounaix

https://www.nature.com/articles/s41598-021-85853-8

This paper reports investigations led on the combination of the refractive index and morphological dilation to enhance performances towards breast tumour margin delineation during conserving surgeries. The refractive index map of invasive ductal and lobular carcinomas were constructed from an inverse electromagnetic problem. Morphological dilation combined with refractive index thresholding was conducted to classify the tissue regions as malignant or benign. A histology routine was conducted to evaluate the performances of various dilation geometries associated with different thresholds. It was found that the combination of a wide structuring element and high refractive index was improving the correctness of tissue classification in comparison to other configurations or without dilation. The method reports a sensitivity of around 80% and a specificity of 82% for the best case. These results indicate that combining the fundamental optical properties of tissues denoted by their refractive index with morphological dilation may open routes to define supporting procedures during breast-conserving surgeries.

Abstract-Terahertz Imaging and Sensing Applications With Silicon-Based Technologies

Philipp Hillger, Janusz Grzyb, Ritesh Jain, Ullrich R. Pfeiffer

https://ieeexplore.ieee.org/document/8576551


Traditional terahertz (THz) equipment faces major obstacles in providing the system cost and compactness necessary for widespread deployment of THz applications. Because of this, the field of THz integrated circuit (THz IC) design in CMOS and SiGe HBT technologies has surged in the last decade. An interplay of advances in silicon process technology, design technique, and microelectronic packaging promises to narrow the gap between the requirements and the reality of system cost and performance of THz components. Furthermore, the scalability, reconfigurability, and signal processing features of silicon technology have initiated research in complex THz ICs that expand the functionality of THz systems; this has enabled new applications, methods, and algorithms. This paper reviews the progress in THz IC research and investigates several realizations of THz imaging and sensing applications with silicon-based components regarding their motivation, system performance, and challenges. THz computed tomography, broadband multicolor imaging, high-resolution FMCW radar imaging, subwavelength resolution near-field imaging, and compressed sensing are presented.

Abstract-Terahertz Imaging and Sensing Applications with Silicon-Based Technologies

Philipp Hillger,  Janusz Grzyb,  Ritesh Jain, Ullrich R. Pfeiffer

https://ieeexplore.ieee.org/document/8576551

Traditional THz equipment faces major obstacles in providing the system cost and compactness necessary for widespread deployment of THz applications. Because of this, the field of THz integrated circuit (THz IC) design in CMOS and SiGe HBT technologies has surged in the last decade. An interplay of advances in silicon process technology, design technique, and microelectronic packaging promises to narrow the gap between the requirements and the reality of system cost and performance of THz components. Furthermore, the scalability, reconfigurability, and signal processing features of silicon technol- ogy have initiated research in complex THz ICs that expand the functionality of THz systems; this has enabled new applications, methods, and algorithms. This paper reviews the progress in THz IC research and investigates several realizations of THz imaging and sensing applications with silicon-based components regarding their motivation, system performance, and challenges. THz computed tomography, broadband multi-color imaging, high-resolution FMCW radar imaging, sub-wavelength resolution near-field imaging, and compressed sensing are presented.