Abstract-Contrast-enhanced continuous-terahertz-wave imaging based on superparamagnetic iron oxide nanoparticles for biomedical applications

Rui Zhang, Liangliang Zhang, Tong Wu, Shasha Zuo, Ruixue Wang, Cunlin Zhang, Jue Zhang, and Jing Fang
https://www.osapublishing.org/oe/abstract.cfm?uri=oe-24-8-7915

We present a novel contrast-enhanced continuous-terahertz-wave imaging modality based on magnetic induction heating of superparamagnetic iron oxide nanoparticles (SPIOs), which yields a highly sensitive increment in the reflection terahertz (THz) signal in SPIO solution upon exposure to an alternating magnetic field. In the differential and relative refection change focal-plane images before and after alternating magnetic field exposure, a dramatic contrast is demonstrated between water with and without SPIOs. This low-cost, simple, and stable contrast-enhanced continuous-THz-wave imaging system is suitable for miniaturization and real-time imaging application.

© 2016 Optical Society of America

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