Abstract-Analysis and inspection techniques for mouse liver injury based on terahertz spectroscopy

Pingjie Huang, Yuqi Cao, Jiani Chen, Weiting Ge, Dibo Hou, and Guangxin Zhang

 Flow chart of injured liver tissue discrimination algorithm based on terahertz spectra.

https://www.osapublishing.org/oe/abstract.cfm?uri=oe-27-18-26014

At present, researchers are exploring biological tissue detection method using terahertz techniques. In this paper, techniques to inspect mouse liver injury by using terahertz spectroscopy were studied. The boxplots were applied to remove abnormal data, and the maximal information coefficient was employed to select crucial features from the absorption coefficient and refractive index spectra. Random Forests and AdaBoost were applied to recognize different levels of liver injury. We found that AdaBoost had better performance on low-level injury classification. This work suggests that terahertz techniques have the potential to detect liver injury at an early stage and evaluate liver treatment strategies.

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